The Top Line

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Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning. 

Recent Episodes
  • Angela Hwang on her pivot from Big Pharma to biotech
    May 9, 2025 – 29:41
  • ElevAAte and the push for East Asian American leaders in biopharma
    May 2, 2025 – 35:59
  • Angus on Angus: A Fierce oncology discussion
    Apr 25, 2025 – 36:58
  • Navigating Trump’s tariffs for pharma
    Apr 18, 2025 – 25:12
  • Q1 biopharma layoff trends, plus expectations for Q2
    Apr 11, 2025 – 11:29
  • A closer look at pharma's top R&D budgets
    Apr 4, 2025 – 11:06
  • What diversity means in medtech
    Mar 28, 2025 – 18:17
  • 5 Key Questions About Precision Patient Marketing—Answered (Sponsored)
    Mar 24, 2025 – 16:16
  • A closer look at pharma’s top patent losses in 2025
    Mar 21, 2025 – 13:58
  • Agenus CMO touts immunotherapy advances on The Top Line
    Mar 17, 2025 – 07:49
  • Breaking down pharma’s fourth-quarter sales boom
    Mar 14, 2025 – 18:36
  • Inside the Future of Aseptic Manufacturing with GRAM (Sponsored)
    Mar 10, 2025 – 22:25
  • Bridging the gap from clinical trials to real-life HIV care (Sponsored)
    Mar 10, 2025 – 16:26
  • A look at biotech's biggest money raisers of 2024
    Mar 7, 2025 – 09:34
  • Research reveals ‘ticking DNA clock’ behind Huntington’s disease
    Feb 28, 2025 – 19:28
  • What were the biggest clinical trial flops of 2024?
    Feb 21, 2025 – 10:17
  • A heartwarming roundup of cardiovascular news and most-loved stories
    Feb 14, 2025 – 12:05
  • Looking ahead at the most anticipated drug launches of 2025
    Feb 7, 2025 – 14:07
  • What to expect from the biotech IPO market in 2025
    Jan 31, 2025 – 34:06
  • Recapping the 2025 J.P. Morgan Healthcare Conference
    Jan 24, 2025 – 20:47
  • Fierce's forecasts for the next year in biopharma
    Jan 17, 2025 – 25:10
  • An additional treatment option with TAGRISSO® (osimertinib) (Sponsored)
    Jan 10, 2025 – 14:25
  • Breaking down the 55 new drug approvals of 2024
    Jan 10, 2025 – 13:03
  • Fierce 50 honorees look ahead: AI, rural health, antibiotic resistance, maternal care and more
    Dec 20, 2024 – 39:41
  • Novo Nordisk’s chief scientific officer looks to the future of GLP-1s
    Dec 13, 2024 – 32:45
  • What can we learn from 2024’s biotech IPOs?
    Dec 6, 2024 – 15:06
  • Meet 2024’s fiercest women in life sciences
    Nov 22, 2024 – 12:30
  • Misconduct and the future of neurodegenerative disease research
    Nov 15, 2024 – 15:29
  • Dig into this year’s Fierce Biotech Graveyard, layoff numbers
    Nov 8, 2024 – 11:51
  • Drug pricing and the 2024 presidential election
    Nov 1, 2024 – 16:34
  • Discover Turbine’s way to build avatars true to patient biology [Sponsored]
    Oct 28, 2024 – 18:15
  • The pulse of the medtech industry
    Oct 25, 2024 – 20:13
  • Where are they now? Catching up with past Fierce 15 honorees
    Oct 18, 2024 – 32:49
  • Revolutionizing gene therapy logistics with Cryoport's Elite solution [Sponsored]
    Oct 14, 2024 – 23:55
  • A revival in neuro therapeutics
    Oct 11, 2024 – 40:29
  • Breaking down BIOSECURE—Industry implications and what comes next
    Oct 4, 2024 – 20:02
  • ESMO, WCLC lung cancer data spark hope—and debate
    Sep 27, 2024 – 23:17
  • Recapping Digital Pharma East 2024
    Sep 20, 2024 – 08:23
  • A closer look at the Fierce 50
    Sep 13, 2024 – 07:24
  • A look at flu vaccine manufacturing and supply in the post-pandemic era
    Sep 6, 2024 – 17:10
  • Driving flu vaccine uptake in the post-pandemic era
    Aug 29, 2024 – 20:46
  • The Crucial Role of HEK293 DNA Quantification in Biotherapeutics [Sponsored by Bio-Rad Laboratories]
    Aug 26, 2024 – 13:42
  • What Chevron’s overturn means for biopharma
    Aug 23, 2024 – 25:15
  • The TROP2 race for supremacy
    Aug 16, 2024 – 24:41
  • A closer look at Fierce Biotech's Fierce 15
    Aug 9, 2024 – 11:17
  • What 'The Next Berlin Patient' and a PrEP’s 100% efficacy mean for HIV drug development
    Aug 2, 2024 – 26:38
  • Fierce 15: Where are they now?
    Jul 26, 2024 – 10:02
  • Former FTC director weighs in on Novo's $16.5B deal with Catalent
    Jul 19, 2024 – 17:18
  • Find out what to expect from the PDA/FDA Joint Regulatory Conference (Sponsored by Parenteral Drug Association)
    Jul 15, 2024 – 13:45
  • A look at Big Pharma’s top-paid CEOs
    Jul 12, 2024 – 10:47
Recent Reviews
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